SurgiMend® is a unique acellular collagen matrix derived from fetal and neonatal bovine dermis. SurgiMend® offers clear advantages over synthetic and other biologic products for soft tissue repair and reconstruction.
SurgiMend is intended for implantation to reinforce soft tissue where weakness exists and for surgical repair of damaged or ruptured soft tissue membranes. SurgiMend is specifically indicated for:
SurgiMend® is a unique acellular collagen matrix derived from fetal and neonatal bovine dermis. SurgiMend® offers clear advantages over synthetic and other biologic products for soft tissue repair and reconstruction.
SurgiMend® offers an abundance of Type III healing collagen. Type III collagen mediates tissue healing while inhibiting scarring. SurgiMend® is derived from young healthy tissue that contains three times more Type III collagen than other acellular dermal matrices.
SurgiMend® is Non-Inflammatory for Better Reinforcement – it does not elicit an acute or chronic foreign body inflammatory. Responses that lead to the implant’s degeneration; SurgiMend® is without preservatives, denatured proteins, artificial chemical crosslinks, cells, lipids, carbohydrates, and other constituents.
SurgiMend® allows for rapid cell repopulation and vascularization. Intraoperatively, patient tissue-building cells and growth factors are sequestered within SurgiMend®. The microporous matrix is rapidly revascularized to support tissue-building and healing for prolonged reinforcement.
| Composition | Native, non-denatured collagen | |||
| Collagen source | Bovine dermis | |||
| Appearance | Flat, dry sheet of uniform thickness and colour | |||
| Storage | Room temperature storage | |||
| Chemical crosslinkers | None | |||
| Rehydration | Approximately 60 seconds in room temperature saline | |||
| Intraoperative handling | Can be trimmed to size wet or dry and placed in any orientation, with either side up | |||
| Pyrogen and viral safety | Non-pyrogenic; manufacturing process includes validated virual-inactivation steps | |||
| Transmissible Spongiform Encephalopathy (TSE) safety | TSE safety certification by Europoean Directorate for the Quality of Medicines, source tissue selected and processed in accordance with strict US and International regulatory requirements | |||
| Sterilisation | Via exposure to ethylene oxide gas; sterility assurance level of 106 with undetectable ethylene oxide residuals | |||
| Tensile strength | 1.0 • | 2.0 •• | 3.0 ••• | 4.0 •••• |
SurgiMend is offered in 1.0mm, 2.0mm, 3.0mm, and 4.0mm thicknesses, providing surgeons with the widest flexibility to choose the most appropriate device thickness, strength, and size for each procedure, technique, and patient.
Trusted for over 15 years, numerous retrospective clinical studies have reported favourable hernia repair outcomes with SurgiMend reinforcement.
Even at 1mm thickness, SurgiMend has been shown to have the strongest uniaxial tensile strength when compared to other major competitors.
Typically surgeons choose SurgiMend 3.0 & 4.0 for open Complex Abdominal Wall Reconstruction. SurgiMend 1.0 is increasingly being used in laparoscopic Abdominal Wall Reconstruction.
| Study | SurgiMend hernia recurrence rate | Materials studied |
|---|---|---|
| Clemens et al.8 | 3.9% | SurgiMend, Strattice |
| Lineaweaver.12 | 6.6% | SurgiMend, AlloDerm and Surgisis |
| Janafaza et al.13 | 5% | SurgiMend and FlexHD |
| Booth et al.9 | 5.8% | SurgiMend, Strattice and AlloDerm |
| Garvey et al.10 | 6.7% | SurgiMend, Strattice and AlloDerm |
| Soares et al.14 | 6% | SurgiMend and Prolene © with hybrid NPWT |
SurgiMend 1.0 & 2.0 can be used in Laparoscopic Abdominal Wall Reconstruction. Thinner sheets of the Accellular dermal matrix allow for easy access during minimally invasive procedures. As well as easy handling and suturing, SurgiMend is compatible with Cyanoacrylate glues enabling fast and secure laparoscopic fixation.
